Complement Dependent Cytotoxicity (CDC) Assay


In 1964, Paul Terasaki and John McClelland (Nature 204:998, 1964) introduced the microlymphocytotoxicity test, known as complement dependent cytotoxicity assay or simply CDC, which became the standard serological assay for HLA typing and cross-matching in clinical tissue transplantation.


 
 
 
 
 
 
International Union of Immunological SocietiesUniversity of South AfricaInstitute of Infectious Disease and Molecular MedicineElizabeth Glazer Pediatric Aids FoundationStellenbosch University