Centrosome

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The central regulator of microtubule cytoskeleton organisation. It consists of a pair of cylindrical centrioles, made up of microtubules. At the start of G1, the single centrosome must be duplicated.

References:

Nigg EA and Stearns T. The centrosome cycle: Centriole biogenesis, duplication and inherent asymmetries. Nature Cell Biology 2011; 13.

Holland AJ et al. Centriole duplication: A lesson in self-control. Cell Cycle 2010; 9(14).

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