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16 September 2024

Recent research has highlighted the role of distinct, disease-specific transcriptional programs in governing goblet cell hyperplasia in asthma and cystic fibrosis…

19 August 2024

In a new study, researchers have identified a potential breakthrough in preventing heart transplant rejection…

07 August 2024

Recent research has shed new light on the relationship between maternal influenza A infection and offspring neurological development…

A 36-year-old man developed two eschars (localized skin lesions) after visiting a rural field in Manzini, Swaziland. He has general weakness, myalgia, night sweats and sore throat. He reports having no rash…

26 July 2024

In a recent study, researchers investigated the elevated incidence of comorbidities post-stroke and if they might share a common immunological root…

Cell-based Cancer Therapies Cytotoxicity is a property of some immune cells to induce lysis of other cells that can be detected as non-functional or transformed. In the recent years, redirecting cytotoxicity in cancer has been the base of cell-based cancer therapies that involve the use of living cells to treat cancer. There are several types Read More

Immunological systems function as soldiers to resist illness, but under some circumstances, the soldiers are reprogrammed to limit immunological response. These specific circumstances appear in cancer and illness.  These reprogrammed immune cells are one of the most exciting areas of study and targeting them can be extremely useful to patients.   These immunosuppressive cells are broadly Read More

11 January 2024

In a recent study, researchers investigate immune cell behavior during human lung development in embryos and fetuses. Track the progression of the fetal immune system and its potential impact on embryonic lung development.

Genetics and Mechanisms of Inflammatory Bowel Disease (IBD) Inflammatory Bowel Disease (IBD) encompasses chronic inflammatory conditions of the gastrointestinal tract, primarily including Crohn’s disease and ulcerative colitis. Genetic factors are key contributors to IBD susceptibility, and understanding candidate genes is crucial to comprehend the disease’s complex pathogenesis. Murine models serve as valuable tools to study Read More

Colon carcinogenesis Carcinogenesis refers to the process by which normal cells transform into cancerous cells, and it involves genetic and epigenetic alterations that disrupt normal cellular functions, leading to uncontrolled cell growth and division. Colon carcinogenesis is a stepwise process initiated by genetic and epigenetic alterations, leading to the activation of oncogenes (e.g., KRAS) and Read More