On World Sepsis Day 2024, survivors of sepsis and patient advocacy groups came together to launch the Paris Declaration, a call to action directed at European leaders. Despite the significant toll that sepsis takes on health systems, it remains severely under-prioritized in Europe. Each year, sepsis affects over 3 million people in Europe and accounts for up to 680,000 deaths. Survivors often face devastating long-term consequences, including organ dysfunction, amputations, cognitive decline, and psychological trauma. Yet, the response from policymakers has been insufficient compared to the gravity of the problem.
Figure 1: Sepsis in Europe
The Sepsis Stronger Together consortium, which includes survivors, patient organizations, and grieving families, emphasized the need for a coordinated European Sepsis Action Plan. While there have been initiatives to tackle antimicrobial resistance (AMR), sepsis—which is responsible for more deaths in Europe—continues to receive little political attention. Infectious diseases and sepsis know no borders, and European countries face similar challenges in preventing and managing sepsis. However, there is little exchange of best practices or harmonized guidelines across the region.
The action plan calls for a focus on early recognition and timely treatment, starting with comprehensive training for healthcare professionals in both primary care and emergency medical services. Public awareness campaigns are also crucial, as 80% of sepsis cases occur outside of hospital settings. Education on infection prevention, hygiene, and the early warning signs of sepsis must be integrated into schools, universities, and workplaces.
Additionally, sepsis should be clearly documented in patient records, and clinical pathways should span the entire patient journey—from initial symptoms at home to rehabilitation. The plan also calls for multidisciplinary care to address the complex needs of sepsis survivors, ensuring access to rehabilitation and psychological support for all patients, including children and older adults.
European governments are urged to recognize the severity of this issue and act swiftly. By investing in research, improving diagnostics, and ensuring access to affordable post-sepsis care, the lives of millions of people affected by sepsis can be improved.
Journal Article: Bracke, Krista, et al. “Sepsis Survivors Call for the Development of a European Sepsis Plan.” The Lancet.
