Clinical Case Studies
Earn HPCSA and SACNASP CPD Points
Infectious Diseases
I have spots and my skin burns
A case of a 10 year old boy with a 3 week history of diarrhoea, vomiting and cough
A case of fever and general malaise
A case of persistant hectic fever
A case of sudden rapid neurological deterioration in an HIV positive 27 year old female
A case of swollen hands
An unusual cause of fulminant hepatitis
Case of a right axillary swelling
Case of giant wart
Case of recurrent meningitis
Case of repeated apnoea and infections in a premature infant
Case of sudden onset of fever, rash and neck pain
Doctor, my sister is confused
Eight month old boy with recurrent infections
Enlarged Testicles
Failure to thrive despite appropriate treatment
Right Axillary Swelling
Severe anaemia in HIV positive child
The case of a floppy infant
Two year old with spiking fevers and depressed level of consciousness
17 year old male with fever and decreased level of consciousness
3 TB Vignettes
A 10 year old girl with a hard palate defect
A case of decreased joint function, fever and rash
Immunotherapy
Keep up while the storm is raging
One Health
Agricultural worker with discomfort, cough and bleeding sputum
Management of Rabies in Côte d’Ivoire
Weakness, myalgia, night sweats and sore throat
Sudden onset of fever, fatigue, myalgia, and headache
Autoimmune Conditions
As I age, the Fc neonatal receptor may still contribute to controlling my disease
Fireworks of autoimmunity from birth
My hands swell and are painful
My eyes cross at twilight
A case of a 3 month old infant with bloody urine and stools
A case of scaly annular plaques
Case of eye injury and decreased vision
My head hurts and I cannot speak?
TB or not TB: a confusing case
A 7 year old with severe muscle weakness and difficulty walking
Why can I not walk today?
14 year old with severe hip pain
A 9 year old girl presents with body swelling, shortness of breath and backache
Drug Responses
A sudden turn of events after successful therapy
Declining CD4 count, despite viral suppression?
Defaulted treatment
25 year old female presents with persistent flu-like symptoms
Gastrointestinal Disorders
A case of persistent bloody diarrhoea
Hypersensitivity
I’ve been coughing for so long
A case of acute fever, rash and vomiting
Adverse event following routine vaccination
Malignancies
A case of cough, wasting and lymphadenopathy
A case of lymphadenopathy and night sweats
Case of enlarged hard tongue
In the Red
Mother to Child Transmission
A high risk pregnancy
Primary Immunodeficiencies
A four year old with immunodeficiency
Young girl with recurrent history of mycobacterial disease
Immunodeficiency and failure to thrive
Case of recurrent infections
An 8 year old boy with recurrent respiratory infections
4 year old boy with recurrent bacterial infections
Secondary Immunodeficiencies
Is this treatment failure or malnutrition
Online Courses
Core Immunology Modules
1. A Snapshot of the Immune System
2. Ontogeny of the Immune System
3. The Innate Immune System
4. MHC & Antigen Presentation
5. Overview of T Cell Subsets
6. Thymic T Cell Development
7. gamma/delta T Cells
8. B Cell Activation and Plasma Cell Differentiation
9. Antibody Structure and Classes
10. Central and Peripheral Tolerance
IUIS Courses
IUIS Immuno-India 2024 Workshop
Introduction and Timetable
Course Materials
Course Recordings
IUIS-FAIS-SAIS Immuno-South Africa 2024
Immuno-SA 2024 Introduction
Zoonotic Infections and One Health
Immune Response to Bacterial Zoonotic Infections
Immune Response to Viral Zoonotic Infections
Immune Response to Parasitic Zoonotic Infections
One Health Approach in Zoonotic Disease Research
Equity, Diversity and Inclusion
Grant Writing
IUIS-SMI-ALACI Immuno-Mexico 2024
Immuno-Mexico 2024 Introduction
Modulation of Peripheral Tolerance
Metabolic Adaptation to Pathologic Milieu
T Cell Exhaustion
Suppression in the Context of Disease
Redirecting Cytotoxicity
Novel Therapeutic Strategies
ImmunoInformatics
Grant Writing
IUIS-ALACI-SMI-ASOCHIN Immuno-Chile 2023
Introduction to Immuno-Chile 2023
Core Modules
Gut Mucosal Immunity
The Microbiome
Gut Inflammation
Viral Infections and Mucosal Immunity
Colorectal Cancer
Inflammatory Bowel Disease
Equity, Diversity, Inclusion in Academia
Grant Writing
IUIS-FIMSA-IIS Immuno-India 2023
Immuno-India 2023 Introduction
Core Modules
Principles of Epigenetic Regulation
Epigenetics Research in Systems Immunology
Epigenetic (De)regulation in Non-Malignant Diseases
Epigenetic (De)regulation in Immunodeficiency and Malignant Diseases
Immunometabolism and Therapeutic Applications of Epigenetic Modifiers
Grant Writing
IUIS-SMI-FAIS Immuno-Morocco 2023
Immuno-Morocco 2023 Introduction
Core Modules
Cancer Cellular Therapies
Cancer Antibody Therapies
Cancer Vaccines
Immunobiology of Leukemia & Therapies
Immune Landscape of the Tumour
Targeting the Tumour Microenvironment
Flow Cytometry
Grant Writing
IUIS-FAIS-SANTHE-ISZ Immuno-Zambia 2022
Immuno-Zambia 2022 Introduction
Core Modules
Immunity to Viral Infections
Immunity to SARS-CoV2
Basic Immunology of HIV
Immunity to Tuberculosis
Immunity to Malaria
Immunity to Schistosomiasis
Immunity to Helminths
Equity, Diversity and Inclusion in Academia
Grant Writing
IUIS-ALACI-ASCAI2 Immuno-Argentina 2022
Immuno-Argentina 2022 Introduction
Core Modules
Dendritic Cells
Trained Innate Immunity
Gamma-Delta T cells
B cells
Natural Killer Cell Memory
Innate Immunity in Viral Infections
Lectures – Innate Immunity
T cells and Beyond
Lectures – Cellular Immunity
Strategies for Vaccine Design
Lectures – Humoral Immunity
Lectures – Vaccine development
Lectures – Panel and Posters
IUIS-Immunopaedia-ALACI Immuno-Cuba 2022
Immuno-Cuba 2022 Introduction
Poster and Abstract Examples
IUIS-FAIS-STI Immuno-Tunisia 2021
Immuno-Tunisia 2021 Introduction
Core Modules
Basics of Anti-infectious Immunity
Inborn Errors of Immunity and Infections
Infection and Auto-Immunity
Pathogen-Induced Immune Dysregulation & Cancer
Understanding of Host-Pathogen Interaction & Applications (SARS-CoV-2)
Day 1 – Basics of Anti-infectious Immunity
Day 2 – Inborn Errors of Immunity and Infections
Day 3 – Infection and Auto-immunity
Day 4 – Pathogen-induced Immune Dysregulation and Cancer
Day 5 – Understanding of Host-Pathogen Interaction and Applications
Student Presentations
Roundtable Discussions
Orientation Meeting
Poster Information
IUIS-ALACI-ACAAI Immuno-Colombia 2021
Immuno-Colombia Introduction
Core Modules
Core Modules Meeting
Overview of Immunotherapy
Check-Points Blockade Based Therapies
Cancer Immunotherapy with γδ T cells
CAR-T, armored CARs and CAR-NK therapies
Anti-cytokines Therapies
Tumor-infiltrating Lymphocytes (TIL)
MDSC Promote Tumor Growth and Escape
Cancer Vaccines
Immunological lab methods for patient’s follow-up
Student Orientation Meeting
Lectures – Week 1
Lectures – Week 2
Student Presentations
Research Project
Closing and Social
IUIS-FAIS Immuno-Algeria 2020
Introduction to Immuno-Algeria 2020
Core Modules
Hypersensitivity Reactions
Immuno-Algeria Programme
Online Lectures – Week 1
Online Lectures – Week 2
Student Presentations – Week 1
Student Presentations – Week 2
IUIS-FAIS Immuno-Ethiopia 2020
Introduction to Immuno-Ethiopia 2020
Core Modules
Neutrophils
Leishmaniasis – Transmission and Epidemiology
Leishmaniasis – Immune Responses
Leishmaniasis – Treatment and Vaccines
Immunity to Helminth Infections
Helminth immunomodulation on co-infections
Immunity to Malaria
Malaria Vaccine Progress
Immunity to Fungal Infections
How to be successful scientist
How to prepare a good academic CV
Previous IUIS Courses
IUIS-FAIS Immuno-Benin
Introduction to Immuno-Benin
Core Modules
Dendritic Cells
Immune Regulation in Pregnancy
Immunity in infants and consequence of preeclampsia
Schistosome infections and impact on Pregnancy
Infant Immunity and Vaccines
Regulation of Immunity & the Microbiome
TGF-beta superfamily in infections and diseases
Infectious Diseases in the Global Health era
Immunity to Malaria
Malaria Vaccine Progress
Immunity to Toxoplasma gondii
Immunity to Helminth Infections
A. melegueta inhibits inflammatory responses during Helminth Infections
Helminth immunomodulation on co-infections
Host immune modulation by Helminth-induced products
Immunity to HIV
Immunity to Ebola
Immunity to TB
Genetic susceptibility in Tuberculosis
Plant Extract Treatment for Diabetes
Grant Writing
IUIS-IDA Immuno-South Africa 2019
Introduction to Immuno-South Africa 2019
Core Modules
Immunity to HIV
Immunity to TB
Immunity to Malaria
Models for Testing Vaccines
Immune Responses to Vaccination
Grant Writing
IDA 2019 Quiz
IUIS-IIS-FIMSA Immuno-Jaipur
Introduction to Immuno-Jaipur
Core Modules
Inflammation and autoinflammation
Central and Peripheral Tolerance
Autoimmunity and Chronic Inflammatory Diseases
Autoimmunity & Dysregulation
Novel Therapeutic strategies for Autoimmune Diseases
Strategies to apply gamma/delta T cells for Immunotherapy
Immune Responses to Cancer
Tumour Microenvironment
Cancer Immunotherapy
Origin and perspectives of CAR T cells
Metabolic checkpoints regulating immune responses
Transplantation
Primary Immunodeficiencies
Regulation of Immunity & the Microbiome
Growing up with Herpes virus
IUIS-ALAI-MEXICO-IMMUNOINFORMATICS
Core Modules
Introduction to IUIS-ALAI-Mexico-ImmunoInformatics
Cancer Immunotherapy
Introduction to Immunization Strategies
Introduction to Immunoinformatics
Omics Technologies
Computational Modeling
Machine Learning Methods
IUIS-FAIS Immuno-Kenya
Introduction to Immuno-Kenya
Core Modules
Viruses hijacking host immune responses
IFNs as 1st responders to virus infections
HBV/HCV & Hepatocellular Carcinoma
Cytokines as biomarkers for HCV
HTLV & T cell Leukemia
HCMV and Cancers
HPV and Cancers
EBV-induced Oncogenesis
Adenoviruses
Immunity to HIV
KSHV and HIV
Cancer Immunotherapy
Ethics in Cancer Research
Sex and gender in Immunity
Flow Cytometry
Group Work
IUIS-ISIA Immuno-Iran
Introduction to Immuno-Iran
Core Modules
Cancer Immunotherapy
Tumour Microenvironment
Immune Regulation in Pregnancy
Introduction to Immunization Strategies
Immunity to Leishmaniasis
Primary Immunodeficiencies
Breaking Tolerance: Autoimmunity & Dysregulation
IUIS-FAIS-SMI Immuno-Morocco
Introduction to Immuno-Morocco
Core Modules
Cancer Epidemiology and Aetiology
Immune Responses to Cancer
Tumour Microenvironment
Pathogens and Cancer
Cancer Immunotherapy
Flow Cytometry
How to be successful scientist
How to prepare a good academic CV
Immunodeficiency and Cancer
IUIS-ALAI Immuno-Brazil
Introduction to Immuno-Brazil
Core Modules
1. Systems Vaccinology
2. Vaccine Development
3. Adjuvants
4. DNA Vaccines
5. Mucosal Vaccines
6. Vaccines for Neurodegenerative Diseases
Grant Writing
IUIS-FAIS Immuno-Gambia
Introduction to Immuno-Gambia
Immuno-Gambia Photos
1. Infant Immunity and Vaccines
2. Dendritic Cells
3. Conventional T Cells
4. gamma/delta T Cells
5. Immunity to Viral Infections
6. Immunity to Helminth Infections
7. Immunity to TB
8. Immunity to Malaria
9. Flow Cytometry
IUIS-IDA Immuno-South Africa 2017
Introduction to Immuno-South Africa
Core Modules
1. Introduction to Immunization Strategies
2. Immune Responses to Vaccination
3. Models for Testing Vaccines
4. Immune Escape
5. Grant Writing
IUIS-FAIS Immuno-Ethiopia
Introduction to Immuno-Ethiopia
1. Neutrophils
2. Dendritic Cells
3. Exosomes
4. gamma/delta T Cells
5. Immunity to Leishmania
6. Immunity to HIV
7. Immunity to Helminth Infections
8. Immunity to TB
9. Grant Writing
IUIS-ALAI-SMI Immuno-Mexico
Introduction to ONCOIMMUNOLOGY-MEXICO
ONCOIMMUNOLOGY-MEXICO Photos
1. Cancer Epidemiology and Etiology
2. T lymphocyte mediated immunity
3. Immune Responses to Cancer
4. Cancer Stem Cells and Tumor-initiating cells.
5. Tumor Microenvironment
6. Pathogens and Cancer
7. Cancer Immunotherapy
8. Flow cytometry approaches in cancer
IUIS-FAIS Immuno-Tunisia
Introduction to the Immunology Course
Immuno-Tunisia Photo
1. Overview of the Immune System
2. Role of cytokines in Immunity
3. Tolerance and autoimmunity
4. Genetics, Epigenetics and immunoregulation
5. Microbes and immunoregulation
6. Inflammation and autoinflammation
7. T cell mediated autoimmune diseases
8. Antibody-mediated autoimmune diseases
IUIS-IDA IMMUNO-SOUTH AFRICA
Introduction to the Immunology Symposium
Immuno-South Africa Photo
1. Antibody Generation by B cells
2. Mucosal Immunity
3. Immunity to TB
4. Immunity to Malaria
5. Immunity to HIV
6. Defining a Biomarker
7. Grant Writing Exercise
IUIS-ALAI Immuno-Colombia
Introduction to the Immunology Course
Immuno-Colombia Photo
1. Overview of Complement
2. Transplantation
3. Immune Regulation in Pregnancy
4. Breaking Tolerance: Autoimmunity & Dysregulation
5. Mucosal Immunity & Immunopathology
6. Regulation of Immunity & the Microbiome
7. Epigenetics & Modulation of Immunity
8. Primary Immunodeficiencies
9. Anti-tumour Immunity
10. Cancer Immunotherapy
Other Courses
12th IDA 2025
12th IDA 2025 Introduction
Immunity to COVID-19
Immunity to TB
Immunity to Malaria
Immunity to HIV
AfriBop 2024
Introduction
Immune Cells
Parasites
NCDs and Multimorbidity
Mosquito Vector Biology
Vaccines and Other Interventions
Autoimmunity
Career Development
Grant Writing
SUN Honours
SUN Honours Introduction
A Snapshot of the Immune System
Ontogeny of the Immune System
The Innate Immune System
MHC & Antigen Presentation
Overview of T Cell Subsets
B Cell Activation and Plasma Cell Differentiation
Antibody Structure and Classes
Cellular Immunity and Immunological Memory
Infectious Diseases Immunology
Vaccinology
Immune Regulation in Pregnancy
Mucosal Immunity & Immunopathology
Central & Peripheral Tolerance
Regulation of Immunity & the Microbiome
Epigenetics & Modulation of Immunity
T cell and Ab-mediated autoimmune diseases
Transplantation
Immunology of COVID-19 Vaccines
Biomarkers
Flow Cytometry
11th IDA 2022
11th IDA 2022 Introduction
Immunity to COVID-19
Immunity to TB
Immunity to HIV
Immunity to Malaria
Grant Writing
AfriBop 2022
Fundamentals of Immunology
Fundamentals of Infection
Integrating Immunology & Infection
Infectious Diseases Symposium
EULAR Symposium
Grant Writing
UCT Advanced Immunology
A Snapshot of the Immune System
Ontogeny of the Immune System
The Innate Immune System
MHC & Antigen Presentation
Overview of T Cell Subsets
Thymic T Cell Development
B Cell Activation and Plasma Cell Differentiation
Antibody Structure and Classes
Central and Peripheral Tolerance
Immune Escape
Immunity to Viral Infections
Immunity to TB
Immunity to Helminth Infections
Introduction to Immunization Strategies
Immune Responses to Vaccination
Infant Immunity and Vaccines
Breaking Tolerance: Autoimmunity & Dysregulation
Primary Immunodeficiencies
Genetics, Epigenetics and immunoregulation
Immunity to Fungal Infections
Regulation of Immunity & the Microbiome
Flow Cytometry
AfriBop 2021
AfriBop 2021 Introduction
Fundamentals of Immunology
Adaptive Immunity
Fundamentals of Infection
Fundamentals of Infection 2
Fundamentals of Infection 3
CHIM
EULAR Symposium
Host pathogen Interaction 1
Host pathogen Interaction 2
Vaccines
Career
Student 3 minute Presentations
Grant Writing
10th IDA 2021
10th IDA 2021 Introduction
Core Modules
Immunity to HIV
Immunity to Malaria
Immunity to TB
Immunity to COVID-19
Day 1 – Lectures
Day 2 – Lectures
Day 3 – Lectures
Day 4 – Lectures
Student Presentations
Afribop 2020
Afribop 2020 Introduction
Fundamentals of Immunology
Adaptive Immunity
Fundamentals of Infection
WT PhD School Lectures 1
EULAR symposium
WT PhD School Lectures 2
Host pathogen interaction 1
Host pathogen interaction 2
Vaccines
Bioinformatics
Grant Writing
Career
Student Presentations
VACFA AAVC 2020
Introduction to VACFA Vaccinology 2020
Overview of Vaccinology
Basic Principles of Immunity
Adverse Events Following Immunization
Targeted Immunization
Challenges Facing Vaccination
Vaccine Stakeholders
Vaccination Questions Answered
Malaria Vaccines
IDA 2018
IDA 2018 Introduction
Immunity to HIV
Regulation of Immunity & the Microbiome
Antibody Structure and Classes
B Cell Activation and Plasma Cell Differentiation
Immunity to TB
Immunity to Malaria
Vaccine Development
Models for Testing Vaccines
Immune Responses to Vaccination
Grant Writing
Immunity to Pathogens
Core Modules
Immune Escape by Pathogens
Immunity to TB
Immunity to Malaria
Immunity to Viral Infections Introduction
Flu, Ebola & SARS
Immunity to HIV
HCMV
HPV
HTLV
HBV/HCV
Biomarkers
TIGRIS
Semester 1
Ontogeny of the Immune System
The Innate Immune System
MHC & Antigen Presentation
Overview of T Cell Subsets
Thymic T Cell Development
B Cell Activation and Plasma Cell Differentiation
Antibody Structure and Classes
Central and Peripheral Tolerance
Basic Immunology of HIV
Immunity to HIV
Antiretroviral Drug Treatments
Responsible Conduct in Research
Methods for Enhancing Reproducibility
Semester 2
Immunology
The Basics of the Immune System
1. A Snapshot of the Immune System
2. Ontogeny of the Immune System
3. The Innate Immune System
4. MHC & Antigen Presentation
5. Overview of T Cell Subsets
6. B Cell Activation and Plasma Cell Differentiation
7. Antibody Structure and Classes
CD Nomenclature
Advanced Immunology
1. Transplantation
2. Central & Peripheral Tolerance
3. Immune Regulation in Pregnancy
4. Breaking Tolerance: Autoimmunity & Dysregulation
5. Mucosal Immunity & Immunopathology
6. Regulation of Immunity & the Microbiome
7. Epigenetics & Modulation of Immunity
8. Inflammation and autoinflammation
9. T cell mediated autoimmune diseases
10. Antibody-mediated autoimmune diseases
Special Focus Area
1. Primary Immunodeficiencies
2. Cancer & Tumours
Cancer Epidemiology and Aetiology
Immune Responses to Cancer
Cancer Stem Cells and Tumour-initiating Cells
Tumour Microenvironment
Pathogens and Cancer
Cancer Immunotherapy
3. Immunity to TB
4. Immunity to Malaria
5. Immunity to HIV
6. Tolerance and Autoimmunity
Historical Fun Facts
Discovery of the Thymus as a central immunological organ
History of Immune Response
History of Immunoglobulin molecules
History of MHC – 1901 – 1970
History of MHC – 1971 – 2011
Webinars
SAIS/Immunopaedia Webinars 2022
IUIS – Immunopaedia – Frontiers Webinars 2022
Metabolic control of T cell differentiation during immune responses to cancer
Microbiome control of host immunity
Shaping of anti-tumor immunity in the tumor microenvironment
The unusual COVID-19 pandemic: the African story
Immune responses to SARS-CoV-2
Adaptive Immunity and Immune Memory to SARS-CoV-2 after COVID-19
IUIS – Immunopaedia – Frontiers Webinars
HIV prevention- antibodies and vaccine development (part 2)
HIV prevention- antibodies and vaccine development (part 1)
Immunopathology of COVID 19 lessons from pregnancy and from ageing
Clinical representation of hyperinflammation
In-depth characterisation of immune cells in Ebola virus
Getting to the “bottom” of arthritis
Immunoregulation and the tumor microenvironment
Harnessing innate immunity from cancer therapy to COVID-19
Flynn Webinar: Immune features associated natural infection
Flynn Webinar: What immune cells play a role in protection against M.tb re-infection?
JoAnne Flynn: BCG IV vaccination induces sterilising M.tb immunity
IUIS-Immunopaedia-Frontiers Webinar on Immunology taught by P. falciparum
SAIS/Immunopaedia Webinars
COVID-19 Cytokine Storm & Paediatric COVID-19
Immunothrombosis & COVID-19
Severe vs mild COVID-19 immunity and Nicotinamide pathway
BCG & COVID-19
COVID-19 Vaccines
Antibody responses and serology testing
Treatment & Diagnostics
Interactive Technique Courses
ELISA
Flow Cytometry Part 1
Flow Cytometry Part 2
Flow Cytometry Part 3
Lateral Flow
SDS-PAGE
Diagnostic Tools
Diagnostic Tests
HIV Infection & Treatment
HIV Life Cycle
ARV Drug Information
ARV Mode of Action
ARV Drug Resistance
Declining CD4 count
TB Drugs
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The Day of Immunology 2021
Ambassador of the Month – 2021
Ambassador of the Month-2020
Ambassador of the Month – 2019
Ambassador of the Month – 2018
Ambassador of the Month – 2017
Course Applications
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Shistosome Population Genetics -J.Cotton
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March 16, 2020
Last Updated
March 16, 2020
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Description
A Comparative Analysis of Oral Contraceptives and Levonorgestrel IUDs
Development of mRNA Rabies Vaccines: A Promising Future
Rabies Control in High-Burden Countries: Universal Pre-Exposure Immunization
Tracking the Lethal Threat An In-Depth Review of Rabies
Acromegaly, Gynaecological Health, and Complementary Therapies: A Multidisciplinary Perspective
Prenatal Diagnosis of Ocular Malformations: Cryptophthalmos, Aphakia, and Corneal Vascularization
Diabetic Retinopathy and Toxoplasma gondii in Pregnant Hispanic Women
Link Between PCOS and Idiopathic Intracranial Hypertension
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